Acromegaly Presenting with Diabetic Ketoacidosis and Diabetes Insipidus

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Acromegaly presenting with diabetic ketoacidosis.

Diabetes in acromegaly is usually non-insulin dependent and is secondary to insulin resistance caused by growth hormone excess. Diabetic ketoacidosis is a result of relative insulin deficiency and is a rare feature of acromegaly. We describe a case of acromegaly presenting with diabetic ketoacidosis. We demonstrate that growth hormone excess can cause diabetic ketoacidosis in the presence of re...

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Malignant somatostatinoma presenting with diabetic ketoacidosis.

High circulating levels of somatostatin (SRIF) were detected in a patient with a metastatic tumour after development of diabetic ketoacidosis (DKA). Fasting insulin and C-peptide levels were markedly suppressed, but plasma glucagon was not suppressed below normal. Progressive cachexia ensued; at autopsy a poorly differentiated non-small cell neuroendocrine carcinoma metastatic to liver was foun...

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Pheochromocytoma presenting as diabetes insipidus.

BACKGROUND Pheochromocytomas are catecholamine producing tumors that classically present with the triad of sweating, palpitations and headache. CASE CHARACTERISTICS 9-year-old boy whose only presenting complaints were polyuria and polydipsia for 2 years. OBSERVATION Routine measurement of blood pressure detected mild hypertension, and subsequent investigations revealed bilateral pheochromoc...

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Diabetic ketoacidosis presenting as neurosurgical emergencies.

Three cases of ketoacidosis in previously unsuspected diabetics are described. Each was admitted to hospital as a neurosurgical emergency. The recognition of this rare presentation is stressed since prompt treatment of the metabolic disturbance rapidly resolves the neurological abnormality.

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Lipemic serum in a toddler with new-onset diabetes mellitus presenting with diabetic ketoacidosis.

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ژورنال

عنوان ژورنال: Journal of the Intensive Care Society

سال: 2014

ISSN: 1751-1437

DOI: 10.1177/175114371401500315